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KMID : 0043319950180010051
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Archives of Pharmacal Research
1995 Volume.18 No. 1 p.51 ~ p.55
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Synthesis of Some new 2-Azolyl-and Azinylthiopyrimidines
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Sherif Laila-Abrahim
Sherif Sherif-M.
Rasha-A.M. Faty
Fattah Abdel-Samei-M. Abdel
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Abstract
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A facile convenient syntheses of the titled compounds, via reacting the precusor 2-amino-2-(pentane-2, 4-dion-3-yithio)-6-phenylpyrimidine-5-carbonitrile (1) with nitrogen nucleophiles and with the carbanions of some active methylene compounds, is reported. Chemical and spectroscopic evidence of the newly syntheised compounds are described.
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